Bioprocess Monitoring & Control

Process Monitoring & Control
Online Monitoring and Control Solutions

Improve your bioprocess yields

It all starts with YSI’s rapid and accurate biosensor technology. With over 40 years of providing rapid, accurate bio-analytical instruments, YSI Life sciences has established a legacy of expertise in various bioprocessing applications, include online monitoring and control, cell culture, fermentation, cell therapy, process R&D, continuous processing and cGMP manufacturing.

YSI analyzers are a proven process analytical technology (PAT) for monitoring critical nutrients, like glucose, sucrose and glutamine. Additionally, YSI analyzers  provide rapid, precise analysis of growth and product-inhibiting metabolites such as lactate and ammonium. Coupled with our online monitoring and control solutions, YSI analyzers are designed to help make your job easier, increase your process knowledge and improve your process yields.

Cell Culture & Fermentation


Bioprocessing requires tight control of nutrients and metabolites to optimize cell growth and maximize product yields. YSI analyzers are the scientist’s PAT technology of choice for measuring important analytes such as glucose, lactate, glutamate, glutamine and more.

  • Monitor up to six chemistries
  • Analytical results in 60 seconds
  • Sample size of 10 – 50 ul
  • High-throughput screen of plates and tubes
  • Configurable for mammalian cell culture or microbial fermentation
  • 21 CFR, Part 11 compliant
  • GAMP®5 compliant

Online Monitoring & Control

YSI 2940 multi-channel monitor

YSI’s online monitoring and control systems are designed to provide simple and reliable online monitoring and control solutions for your bioreactor process. Closed loop monitoring and control of critical nutrients are easily achieved for any scale of operation or type of bioreactor.

  • Automated bioreactor sampling
  • Real-time analysis
  • Interfaces with any size or type of bioreactor
  • Aseptic operation
  • Feed control of up to 2 feed pumps
  • Connectivity options for SCADA, DAS or LIMS
  • CIP/SIP compatible